Taking andrographis orally, either on its own or combined with other herbal ingredients, may help ease symptoms such as cough and sore throat in individuals suffering from the common cold. However, there is not enough evidence to confirm whether it can prevent colds altogether.

Daily use of andrographis extract by mouth may help lessen knee pain and stiffness in people dealing with mild to moderate osteoarthritis.

Taking andrographis orally each day may offer similar relief from fever and discomfort caused by tonsillitis as acetaminophen (Tylenol).

Consuming andrographis extract daily for 8 weeks may help improve symptoms of ulcerative colitis, showing effectiveness comparable to the medication mesalamine.